It is Generally the Case That

How Much Is That Laptop ? It Depends on the Color of the Case . And That ' s

As economists use the term, price discrimination means charging some buyers more than others for essentially the same product or service. Is it a bad thing? Buyers paying the higher prices understandably resent the practice. They might thus be surprised to learn that it often enables them to enjoy both lower prices and higher quality than would be possible if sellers charged the same price to e...

Vaccination against shigellosis: is it the path that is difficult or is it the difficult that is the path?

Following several decades of research, there is not yet a convincing vaccine against shigellosis. It is still difficult, in spite of the breadth of strategies (i.e. live attenuated oral, killed oral, subunit parenteral) to select an optimal option. Two approaches are clearly emerging: (i) live attenuated deletion mutants based on rational selection of genes that are key in the pathogenic proces...

RNA catalysis--is that it?

Ribozymes are RNA molecules that accelerate chemical reactions, enzymes that happen to be made of RNA rather than protein. Aside from the chemical challenge of trying to explain how a nucleic acid can do that, why should anyone care? Although these species created a lot of interest when the RNA journal began 20 years ago, they have slipped out of fashion more recently, and some may think RNA ca...

it is a great pleasure that we managed to publish the third issue ...

Take two NSAIDs and call on your satellite cells in the morning IT IS GENERALLY AGREED

IT IS GENERALLY AGREED that successful skeletal muscle regeneration following intense exercise or injury is facilitated by the protein synthesis machinery and the recruitment of myogenic stem (satellite) cells. Upstream activation of these processes, however, is poorly understood. A growing body of evidence suggests cyclooxygenase (COX) activity plays an important role, as COX inhibition via no...